Dr. Oz – Vitamin E Tocotrienols Recommended
Recently, tocotrienol.org wrote a summary of Dr. Oz’s recommendation of Vitamin E tocotrienols as one of 2013 supplements of the year. But, is Dr. Oz working with outdated information?
Kyani Science’s Dr. Barry Tan (one of the leading scientists who has discovered the most recent source of Vitamin E tocotrienol and works exclusively with Kyani with his latest discovery of Vitamin E tocotrienols from the annatto bush) states that his latest discovery of Vitamin E tocotrienols from the annatto bush is the highest quality form of Vitamin E and it is tocopheral free.
Let’s take a look at the summary from tocotrienol.org of Dr. Oz’s opinion on Vitamin E tocotrienols from palm fruit (Dr. Tan’s 2nd discovery):
Dr. Oz Recommends Red Palm Oil Due To Vitamin E Tocotrienols Unique Health Benefits
New Jersey, USA – Touted as the “Super Vitamin E”, tocotrienols from palm fruit oil with unique health benefits, has led the famed TV personality Dr. Oz to call red palm oil as his most miraculous find for 2013 to address the aging process
In his recent television show, Dr. Oz together with alternative health expert Bryce Wylde, explained why they think red palm oil with tocotrienols and mixed carotene is on top of the other oils in terms of nutritional and unique health benefits.
The health benefits of red palm oil were attributed to two very powerful phytonutrients – carotenes and tocotrienols. They went on to explain how the tocotrienols provide protection against age-related brain and heart diseases such as Alzheimer’s disease and dementia; arterial blockage and unhealthy level of LDL-cholesterol. Furthermore, study shows that women who consumed red palm oil enriched with tocotrienols resulted in the loss of belly fat as red palm oil is metabolized immediately and not stored in the abdomen.
“Did you know that palm trees contain an ancient remedy that can slow down the aging process, fight belly fat and combat heart disease?” asks Dr. Oz as he and Bryce Wylde, alert viewers to what they believe may be the biggest nutritional find of 2013.
Tocotrienols are the primary form of vitamin E in the mesocarp (flesh) of the palm fruits (Elaeis guineensis). In fact, crude palm oil contains the highest amount of tocotrienols in nature, mainly consisting of gamma-tocotrienol and alpha-tocotrienol – tocotrienols that research has shown possess powerful neuroprotective, antioxidant, anti-cancer and cholesterol lowering properties.
“Carotech extracts both the carotenoids and tocotrienols from red palm oil and delivers them in concentrated forms to dietary supplement companies. As mentioned in Dr Oz’s show, these phytonutrients especially the full spectrum palm tocotrienol complex are proven by science to have significant unique health benefits such as protection against age-related neurodegeneration, heart, liver as well as skin health,” says Mr. WH Leong, Vice President, Carotech Inc.
“Recent published studies using Tocomin SupraBio®, the patented and bioenhanced natural full spectrum palm tocotrienol complex support these unique health benefits. We are excited that Dr Oz embraces this super vitamin E with unique health benefits, not shown by the regular tocopherol vitamin E. And we expect more new clinical trial results to be published soon which will further strengthen tocotrienol’s position as the Super Vitamin E.” added Mr. Leong.
Whole Foods Magazine Interviews Dr. Barrie Tan Who Describes What Is in Vitamin E Tocotrienols
Interestingly, as you will read below. Dr. Tan actually was the first to patent the commercial extraction process of Vitamin E tocotrienols and Dr. Tan founded Carotech (the company mentioned above in the Dr. Oz Vitamin E tocotrienols interview) in 1988 and sold it in the early ’90s. Read this excerpt from the interview discussing Vitamin E tocotrienols (read the full article):
Passwater: Dr. Tan, for our new readers, could you review your history with vitamin E tocotrienols?
Figure 1: Annatto flowers (Bixa orellana).
Tan: My first acquaintance with vitamin E tocotrienols was during my biochemical research with carotenoids as a professor at the University of Massachusetts, Amherst. At the time, I was studying palm carotenes, and noticed a nearly colorless oil, which we later identified to be largely tocotrienols. The discovery was followed by a patent on the commercial extraction process and my founding of Carotech in 1988, which today is a major supplier of palm-derived products, including tocotrienols. After the sale of Carotech in the early 90s, I continued to explore tocotrienol extraction from rice bran, a technology later adopted by Eastman-Kodak. As did Sean Connery in the Medicine Man movie (1992), I stumbled onto my next discovery: the unique source of tocotrienols in the South American annatto plant with its fragile, yet beautiful pastel white or pinkish flowers and characteristic bundle-like filaments containing anthers (see Figure 1).
It takes approximately a month for the annatto plant to see its robust buds become immature greenish pods. The plant was named Bixa orellana after the Spanish explorer Francisco de Orellana, who discovered it in the Amazonia in the 1500s. The British later nicknamed this the “lipstick” plant because of the intense maroon color. It was first introduced to the United States as a food colorant about 150 years ago.
It takes another two months for the tiny pods to mature and grow to larger ones, about the size of figs. They graduate from stunning green, yellow, to red pods, and finally open when fully ripe to reveal the annatto beans (see Figure 2). These beans contain the most powerful vitamin E antioxidants of Amazonia known to date. Annatto remains the first and only true source of nature-derived vitamin E that supplies tocotrienols without tocopherols.
Figure 2: Annatto pods (“Lipstick” tree).
Passwater: So, the main natural sources of tocotrienols are palm, rice and annatto?
Tan: Yes, but the tocotrienol composition in these sources varies. Palm and rice tocotrienol sources typically contain 25–50% tocopherols—mainly as alpha-tocopherol—while annatto is tocopherol-free vitamin E and solely composed of delta- and gamma-tocotrienol (see Figure 3).
Figure 3: Sources and composition of natural tocotrienols.
Serious About Finding Ways to Reduce Inflammation?
Much of the research on vitamin E has focused on alpha-tocopherol, while studies into tocotrienols account for less than 1% of all research into vitamin E. However, Kyani’s Vitamin E tocotrienols researcher Dr. Barrie Tan has been leading the way in helping people better understand what is in Vitamin and why Vitamin E tocotrienols represent one of the newest cutting edge ways to reduce inflammation.
More recently, Vitamin E tocotrienols have reached a new measure of scientific recognition, with nearly 30% of peer-reviewed research articles on the vitamin published within the last two years (2009–2010). The first-ever scientific compilation of tocotrienol research, Tocotrienols: Vitamin E Beyond Tocopherols, was published in 2008 by CRC and AOCS Press, while a second edition has been approved for publication in May 2012. Tocotrienols are named by analogy to tocopherols (from Greek words meaning to bear a pregnancy (see tocopherol); but with this word changed to include the chemical difference that tocotrienols are trienes, meaning that they share identical structure with the tocopherols except for the addition of three double bonds to their side chains (Read More).
How Important Is Vitamin E?
Vitamin E refers to a group of eight fat-soluble compounds that include both tocopherols and Vitamin E tocotrienols.Of the many different forms of vitamin E, γ-tocopherol is the most common in the North American diet. γ-Tocopherol can be found in corn oil, soybean oil, margarine, and dressings. In the North American diet, α-tocopherol, the most biologically active form of vitamin E, is the second-most common form of vitamin E. This variant can be found most abundantly in wheat germ oil, sunflower, and safflower oils.
What is the main function of Vitamin E tocotrienols?
Vitamin E Tocotrienol is more effective antioxidant than tocopherol because its unsaturated side chain facilitates better penetration into saturated fatty layers of the brain and liver. Vitamin E Tocotrienols can lower tumor formation, DNA damage and cell damage. Below are studies in which Vitamin E tocotrienols have proven their effectiveness (source):
- Vitamin E Tocotrienols and stroke-induced Injuries – In the peer-reviewed Stroke journal (Oct 2005), oral supplementation of a natural full spectrum palm tocotrienol complex to spontaneously hypertensive rats led to increased tocotrienol levels in the brain. The rats, supplemented with tocotrienols, showed more protection against stroke-induced injury compared to controls (non-supplemented group).
- Vitamin E Tocotrienols and pancreatic cancer – In a 2009 in-vitro study, scientists at Department of Nutrition and Food Sciences, Texas Woman’s University evaluated the impact of d-delta-tocotrienol, a potent vitamin E isomer, on human MIA PaCa-2 and PANC-1 pancreatic carcinoma cells and BxPC-3 pancreatic ductal adenocarcinoma cells. They concluded suppression of mevalonate pathway activities, be it by modulators of HMG CoA reductase (statins, tocotrienols, and farnesol), farnesyl transferase (farnesyl transferase inhibitors), and/or mevalonate pyrophosphate decarboxylase (phenylacetate) activity, have a potential in pancreatic cancer chemotherapy. Moreover, a Phase I dose-escalating clinical study evaluating the effect of pure δ-tocotrienol towards individuals with pancreatic cancer is running from 2009 to 2013 at the Moffitt Cancer Centre, and is the first tocotrienol study that is being clinically evaluated in humans towards cancer.
- Vitamin E Tocotrienols and breast cancer – In the 1990s, studies showed tocotrienols are the components of vitamin E responsible for growth inhibition in human breast cancer cells in vitro,through estrogen-independent mechanisms. Tocotrienols work synergistically with tamoxifen, a commonly used breast cancer medicine, in killing cancer cells.
- Vitamin E Tocotrienols and prostate cancer – various research studies suggest that both δ- and γ-tocotrienol potently suppressed prostate cancer cell proliferation. In one study,the antiproliferative effect of γ-tocotrienol act through multiple-signalling pathways (NF-B, EGF-R and Id family proteins). In addition, the same study demonstrated the anti-invasion and chemosensitisation effect of γ-tocotrienol against PCa cells.
- Vitamin ETocotrienols and skin cancer – In a 2009 study at the Li Ka Shing Faculty of Medicine, The University of Hong Kong, scientists found reduction in skin cancer cells when treated with gamma-tocotrienol with chemotherapy drugs. For the first time, researchers recorded the anti-invasion and chemonsensitization effect of gamma-tocotrienol against human malignant melanoma cells.
- Vitamin E Tocotrienols and cholesterol reduction – In 1993, American scientists conducted a double-blind placebo controlled study of 50 volunteers at the Kenneth Jordan Heart Foundation and Elmhurst Medical Center. Their results suggested that tocotrienols (from palm and rice) could ease clogged arteries. Seven high cholesterol patients with narrowing arteries experienced reversal of arterial blockage of the carotid artery after consuming tocotrienols, while in two the condition worsened. This was compared to the control group, where none improved and ten worsened. Tocotrienols, especially δ- and γ-tocotrienols, were shown to be effective nutritional agents in treating high cholesterol.
- Tocotrienols and diabetes – In 2009, animal trials carried out in India and Malaysia revealed palm tocotrienols improved blood glucose, dyslipidemia and oxidative stress in diabetic rats. It is able to prevent the progression of vascular wall changes occurring in DM.
- Tocotrienols and radiation countermeasures – In the past six years, the Armed Forces Radiobiology Research Institute (AFRRI) has performed extensive research on tocotrienol —a form of vitamin E — as radiation countermeasure agent. Tocotrienols occur naturally as four distinct molecules designated α-, β-, γ- and δ-tocotrienol. Of these, δ- and γ-tocotrienol are the most effective radioactive countermeasure agents.
Kyani Sunset is a proprietary blend of Wild Alaskan Sockeye Salmon omega 3 fish oils (extracted with a patented process that results in a mercury-free fish oil supplement) and Vitamin E tocotrienols from the annatto bush. As you have discovered by reading this article on Vitamin E tocotrienols and understanding what is in Vitamin E, you’ve probably realized that Dr. Oz’s recommendation for Vitamin E tocotrienols based upon red palm oil is very outdated. That form of Vitamin E tocotrienols was discovered in 1988 – nearly 25 years ago!
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Yes, you read that right. You can try the Kyani Sunset blend of Vitamin E tocotrienols risk-free. If you don’t like it and don’t feel it is one of the best ways to reduce inflammation, then they will give you 100% of your money back. I can’t think of a safer offer and all the risk is on Kyani.
But, when you have such a high quality product like the Kyani Sunset Vitamin E tocotrienols, there is very little risk. Purchase Vitamin E tocotrienols as a part of the Kyani Health Triangle. We believe you’ll love them and want more of the Kyani Vitamin E tocotrienols!
* Once you select your country, choose a product category and this will then give you the option to purchase the Kyani Sunset product individually, although we do recommend the full Kyani Health Tri Pack as the best way to ensure optimal results.
** Information contained herein is not intended to be taken as medical advice nor are any therapeutic or medical claims made.